Synergistic Mechanism of Gene Expression and Pathways between Jasminoidin and Ursodeoxycholic Acid in Treating Focal Cerebral Ischemia–Reperfusion Injury

Jun Liu, Cai‐Xiu Zhou, Zhanjun Zhang, Liying Wang, Zhiwei Jing, Zhong Wang

CNS Neuroscience & Therapeutics · 2012 · 27 citations · 31 references

Abstract

These findings may suggest that jasminoidin is the major component of the combination, and the combination plays an important role of the synergistic effect in up-regulating expression of gene Hspa1a, genes Fgf12, Rarα, Map3k4 and down-regulating gene PXN, as well as activating P53 pathway.

References

31