Matrix deactivation: A general approach to improve stability of unstable and reactive pharmaceutical genotoxic impurities for trace analysis

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

Lutz Müller, Robert J. Mauthe, Christopher M. Riley et al. · Regulatory Toxicology and Pharmacology · 2006 · 461 citations

Pharmacy, Pharmaceutics, Toxicology +12

A generic approach for the determination of trace hydrazine in drug substances using in situ derivatization-headspace GC–MS

Mingjiang Sun, Lin Bai, David Q. Liu · Journal of Pharmaceutical and Biomedical Analysis · 2008 · 205 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +10

Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium

Mingjiang Sun, Silvia C. Finnemann, Maria Febbraio et al. · Journal of Biological Chemistry · 2005 · 160 citations · Full text

Life Sciences, Biochemistry, Ophthalmology +12

Coordination-Ionspray-MS (CIS-MS), a Universal Detection and Characterization Method for Direct Coupling with Separation Techniques

Ernst Bayer, Petra Gfrörer, Claus Rentel · Angewandte Chemie International Edition · 1999 · 119 citations

Pharmacy, Chemistry, Analytical Chemistry +13

A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization–headspace–gas chromatography–mass spectrometry

Roberto Alzaga, R. W. Ryan, Karen Taylor-Worth et al. · Journal of Pharmaceutical and Biomedical Analysis · 2007 · 82 citations

Natural Sciences, Chemistry, Pharmaceutical Analysis +14