Synthetic Communications · 1996 · 19 citations · 7 references
Diversity Oriented SynthesisNatural Product SynthesisBioorganic ChemistryEngineeringBiochemistryNatural SciencesDiversity-oriented SynthesisCorresponding Substituted Pyrimidin-2′-onesOrganic ChemistryChemistryPharmacology17-Oxo-5-androsten-3β-yl AcetateSynthetic ChemistryBiomolecular EngineeringSteroidal Pyrimidines
Abstract Selected aryl aldehydes were treated with 17-oxo-5-androsten-3β-yl acetate (I) to give the corresponding 16-arylidene 17-oxo-5-androsten-3β-yl acetates(IIa-e). Condensation of these chalcones with urea revealed the formation of the corresponding substituted pyrimidin-2′-ones (IIIa-e) respectively.
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