Heterocycles. Part I. A new route to the synthesis of substituted 2‐aminopyrimidines

Abstract

Abstract Heterocyclic aldehydes (A) reacted with alkyl aryl ketones (B) to give the corresponding 1,3‐diaryl‐2‐propen‐1‐ones (Ia‐1). Condensation of these chalcones with guanidine produced the corresponding 2‐amino‐4,6‐diarylpyrimidines (IIa‐1). The structure of all products was substantiated by chemical and spectroscopic methods.