The anti-angiogenic herbal extracts Ob-X from<i>Morus alba</i>,<i>Melissa officinalis</i>, and<i>Artemisia capillaris</i>suppresses adipogenesis in 3T3-L1 adipocytes

Abstract

These results suggest that the anti-angiogenic herbal composition Ob-X inhibits differentiation of preadipocytes into adipocytes. These events may be mediated by changes in the expression of genes involved in lipogenesis, angiogenesis, and the MMP system. Thus, by reducing adipogenesis, anti-angiogenic Ob-X provides a possible therapeutic approach for the prevention and treatment of human obesity and its related disorders.