Antibiotics from Gliding Bacteria, LXXIII Indole and Quinoline Derivatives as Metabolites of Tryptophan in Myxobacteria

Abstract

Abstract Two groups of 3‐substituted indole 1, 6–9 as well as 4‐substituted quinoline derivatives 2–5 and harman ( 10 ) were isolated from various species and genera of myxobacteria. They were identified by their spectroscopic data. Some of the metabolites show moderate antifungal activity. Their biosynthetic origin in myxobacteria was demonstrated for 1, 2 , and 3 by incorporation of L ‐[1'‐ 14 C]tryptophan.