Concepedia

The −14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activity

Tine G.K. Jensen, Anke Liebert, Rikke Lewinsky, Dallas M. Swallow, Jørgen Olsen, Jesper T. Troelsen

Human Genetics · 2011 · 56 citations · 42 references

DOI

Concepts

References

42

Convergent adaptation of human lactase persistence in Africa and Europe

Sarah A. Tishkoff, Floyd A. Reed, Alessia Ranciaro et al. · Nature Genetics · 2006 · 1.6K citations · Full text

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Genetic Signatures of Strong Recent Positive Selection at the Lactase Gene

Todd Bersaglieri, Pardis C. Sabeti, Nick Patterson et al. · The American Journal of Human Genetics · 2004 · 1.2K citations · Full text

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Identification of a variant associated with adult-type hypolactasia

Nabil Enattah, Timo Sahi, Erkki Savilahti et al. · Nature Genetics · 2002 · 1.1K citations

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The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

Richard A. Sturm, Gautam Das, Winship Herr · Genes & Development · 1988 · 672 citations · Full text

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Lactose digestion and the evolutionary genetics of lactase persistence

C Ingram, Charlotte A. Mulcare, Yuval Itan et al. · Human Genetics · 2008 · 503 citations

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