Alcaloïdes Pipéridiniques II. Structures de la Prosopine et de la Prosopinine, Alcaloïdes du Prosopis Africana (Guill. et Perr.) Taub. [1]

Abstract

Abstract In a preliminary note [1] we established the plane structure of the prosopine 1,2‐hydroxymethyl 3‐hydroxy 6‐dodecyl 11°‐hydroxypiperidine and the prosopinine 8, 2‐hydroxymethyl 3‐hydroxy 6‐dodecyl 10°‐keto piperidine, alkaloids isolated from Prosopis africana (Guill & Perr) Taub. This paper contains the study of the reduction products of the pyrrolidine 18 b and the establishment of the relative and absolute configurations of these two alkaloids. The experimental part involves the details for the determination of these structures and also the extraction method of these two alkaloids as well as the new alkaloids: prosophylline, prosafrine and the prosafrinine isolated from leaves of P. africana and isoprosopinines A and B extracted from roots and stem bark of the same plant. The establishment of the structure of the new five alkaloids is the subject of the next paper.