Verbindungen mit dem 1,3‐dimethyl‐1,3,2‐diazaphosphetidin‐4‐on‐Grundgerüst: Synthese von 1,3‐Dimethyl‐1,3,2‐diazaphosphetidin‐4‐on‐2‐oxid‐Derivaten

Abstract

Compounds Involving the 1,3‐Dimethyl‐1.3,2‐diazaphosphetidin‐4‐one Framework Synthesis of 1,3‐Dimethyl‐1.3,2‐diazaphosphetidin‐4‐one 2‐Oxide Derivatives The oxidation of 1,3,2‐diazaphosphetidinones 3, 4, 7–9 to the respective P ‐oxides using NO 2 ( 3→5 and 4→6 ) or (Me 3 SiO) 2 ( 7→10, 8→11 , and 9→12 ) is described. Other diazaphosphetidinone P ‐oxides 13–15 are obtained by the reaction of N,N′‐ dimethylurea with phosphonic dichlorides in the presence of triethylamine as an HCl acceptor. The compounds 5, 6, 10 – 15 contain the novel structural element, involving λ 4 P. The reaction of 10 and 15 with methanol leads to the formation of the acyclic methyl esters MeOP‐(O)(Y)N(Me)C(O)N(Me)H ( 20 ) [Y = N(CH 2 ) 4 ] and ( 21 ) [Y = Ph].