Effect of Plasma Protein Binding of Drugs on Duration and Intensity of Pharmacological Activity

Blood Levels of Drug at the Equilibrium State after Multiple Dosing

John G. Wagner, Jack I. Northam, C. Alway et al. · Nature · 1965 · 246 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

PREDNISONE SIDE-EFFECTS AND SERUM-PROTEIN LEVELS

GeorgeP. Lewis, WilliamJ. Jusko, ChristopherW. Burke et al. · The Lancet · 1971 · 238 citations

Life Sciences, Pharmacology, Pharmacotherapy +8

Serum Concentrations of Free Diphenylhydantoin and their Relationship To Clinical Intoxication

Harold E. Booker, Barbara A. Darcey · Epilepsia · 1973 · 142 citations

Medicine, Pharmacology, Toxicology +13

Pharmacokinetics of drugs in patients with the nephrotic syndrome.

R Gugler, Don W. Shoeman, David H. Huffman et al. · Journal of Clinical Investigation · 1975 · 141 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Effect of Plasma Protein Binding on Elimination of Warfarin

Gerhard Levy, Avraham Yacobi · Journal of Pharmaceutical Sciences · 1974 · 125 citations

Medicine, Pharmacology, Pharmacotherapy +12