Valproic Acid Suppresses Interleukin-1ß-induced Microsomal Prostaglandin E<sub>2</sub>Synthase-1 Expression in Chondrocytes Through Upregulation of NAB1 - Concepedia

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Valproic Acid Suppresses Interleukin-1ß-induced Microsomal Prostaglandin E<sub>2</sub>Synthase-1 Expression in Chondrocytes Through Upregulation of NAB1

DOI Full Paper Access

13

Citations

43

References

2011

Year

Nadia Zayed, Fatima Ezzahra El Mansouri, N. Chabane, Mohit Kapoor, Johanne Martel‐Pelletier, Mohamed Benderdour, Jean‐Pierre Pelletier, Nicolas Duval, Hassan Fahmi

The Journal of Rheumatology

Abstract

VA inhibited IL-1-induced mPGES-1 expression in chondrocytes. The suppressive effect of VA was not due to reduced expression or recruitment of Egr-1 to the mPGES-1 promoter and involved upregulation of NAB1.

References

	Year	Citations

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