Concepedia

Temporal dissection of p53 function in vitro and in vivo

Maria A. Christophorou, Dionisio Martı́n-Zanca, Laura Soucek, Elizabeth R. Lawlor, Lamorna Brown Swigart, Emmy W. Verschuren, Gérard I. Evan

Nature Genetics · 2005 · 185 citations · 20 references

DOI

Concepts

References

20

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

, , +15

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

, , +14

p53 is required for radiation-induced apoptosis in mouse thymocytes

Scott W. Lowe, Earlene M. Schmitt, Sallie W. Smith et al. · Nature · 1993 · 2.9K citations

, , +14

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

Trevor D. Littlewood, David C. Hancock, Paul S. Danielian et al. · Nucleic Acids Research · 1995 · 789 citations · Full text

, , +16