Oncogenic BRAF regulates β-Trcp expression and NF-κB activity in human melanoma cells

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

Ebrahim Zandi, David M. Rothwarf, Mireille Delhase et al. · Cell · 1997 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways

Emmanuel Dejardin, Nathalie Droin, Mireille Delhase et al. · Immunity · 2002 · 916 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation.

Kapaettu Satyamoorthy, Gang Li, Michelle R. Gerrero et al. · PubMed · 2003 · 435 citations

Medicine, Cancer Biology, Oncology +17

Suppression of BRAF(V599E) in human melanoma abrogates transformation.

Sunil R. Hingorani, Michael A. Jacobetz, Gavin P. Robertson et al. · PubMed · 2003 · 416 citations

Medicine, Molecular Biology, Oncology +16

Mutant V599EB-Raf Regulates Growth and Vascular Development of Malignant Melanoma Tumors

Arati Sharma, Nishit R. Trivedi, Melissa Zimmerman et al. · Cancer Research · 2005 · 319 citations

Life Sciences, Genetics, Oncology +16