Concepedia

Latent NOTCH3 epitopes unmasked in CADASIL and regulated by protein redox state

Xiaojie Zhang, Soo Jung Lee, Kelly Z. Young, David A. Josephson, Michael D. Geschwind, Michael M. Wang

Brain Research · 2014 · 16 citations · 16 references

DOI

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16

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

Anne Joutel, Christophe Corpechot, Anne Ducros et al. · Nature · 1996 · 2.1K citations

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Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients

Anne Joutel, Katayoun Vahedi, Christophe Corpechot et al. · The Lancet · 1997 · 684 citations

, , +13

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

Anne Joutel, F. Andreux, Swann Gaulis et al. · Journal of Clinical Investigation · 2000 · 600 citations · Full text

, , +14

The structure of a Ca2+-binding epidermal growth factor-like domain: Its role in protein-protein interactions

Zihe Rao, Penny A. Handford, Mark Mayhew et al. · Cell · 1995 · 344 citations · Full text

, , +14

Abnormal recruitment of extracellular matrix proteins by excess Notch3ECD: a new pathomechanism in CADASIL

Marie Monet-Leprêtre, Iman Haddad, Céline Baron‐Menguy et al. · Brain · 2013 · 216 citations · Full text

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