Metal ion promoted attack of an alcohol on a phosphate diester: modelling the role of metal ions in RNA self-splicing reactions

Reaction mechanism of alkaline phosphatase based on crystal structures

Eunice E. Kim, Harold W. Wyckoff · Journal of Molecular Biology · 1991 · 950 citations

Biochemistry, Alkaline Phosphatase, Structure-function Enzyme Kinetics +2

Metal ion catalysis in the Tetrahymena ribozyme reaction

Joseph A. Piccirilli, Joseph S. Vyle, Marvin H. Caruthers et al. · Nature · 1993 · 386 citations

Inorganic Chemistry, Engineering, Biochemistry +7

The catalytic carboxyester hydrolysis by a new zinc(II) complex with an alcohol-pendant cyclen (1-(2-hydroxyethyl)-1,4,7,10-tetraazacyclododecane): A novel model for indirect activation of the serine nucleophile by zinc(II) in zinc enzymes

Tohru Koike, Satoko Kajitani, Ikushi Nakamura et al. · Journal of the American Chemical Society · 1995 · 184 citations

Zinc Enzymes, Indirect Activation, Catalytic Carboxyester Hydrolysis +14

Functional group convergency in a binuclear dephosphorylation reagent

David H. Vance, Anthony W. Czarnik · Journal of the American Chemical Society · 1993 · 137 citations

Altmetrics, Molecular Sciences, Engineering +14

Phosphodiester Hydrolysis by a New Zinc(II) Macrocyclic Tetraamine Complex with an Alcohol Pendant: Elucidation of the Roles of Ser-102 and Zinc(II) in Alkaline Phosphatase

Eiichi Kimura, Yorimitsu Kodama, Tohru Koike et al. · Journal of the American Chemical Society · 1995 · 132 citations

Aldo-keto Reductase, Chemical Analysis, Altmetric Attention Score +16