Concepedia

Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine

Patricia Boya, Rosa A. González‐Polo, Delphine Poncet, Karine Andréau, Helena L.A. Vieira, Thomas Roumier, Jean‐Luc Perfettini, Guido Kroemer

Oncogene · 2003 · 381 citations · 36 references

DOI

Concepts

References

36

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

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Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng et al. · Science · 2001 · 3.9K citations · Full text

, , +17

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

Naoufal Zamzami, Philippe Marchetti, Maria Castedo et al. · The Journal of Experimental Medicine · 1995 · 1.6K citations · Full text

, , +12

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

Atan Gross, Jennifer Jockel, Michael C. Wei et al. · The EMBO Journal · 1998 · 1.1K citations · Full text

, , +15

Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis

Éric Daugas, Santos A. Susín, Naoufal Zamzami et al. · The FASEB Journal · 2000 · 779 citations

, , +15