Concepedia

Camptothecin-20-PEG ester transport forms: the effect of spacer groups on antitumor activity

Robert A. Greenwald

Bioorganic & Medicinal Chemistry · 1998 · 104 citations · 26 references

DOI

Concepts

References

26

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata<sup>1,2</sup>

Monroe E. Wall, Mansukh C. Wani, Clarence Cook et al. · Journal of the American Chemical Society · 1966 · 2.2K citations

, , +8

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

, , +10

A novel connector linkage applicable in prodrug design

Philip L. Carl, Prasun K. Chakravarty, John A. Katzenellenbogen · Journal of Medicinal Chemistry · 1981 · 344 citations

, , +7

Polymeric Antitumor Agents on a Molecular and on a Cellular Level?

Leo Gros, Helmut Ringsdorf, Hans Schupp · Angewandte Chemie International Edition in English · 1981 · 318 citations

, , +14

Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity

Abraham E. Mathew, Magdalena R. Mejillano, Jyoti P. Nath et al. · Journal of Medicinal Chemistry · 1992 · 250 citations

, , +8