Vibrating Membrane Devices Deliver Aerosols More Efficient than Standard Devices: A Study in a Neonatal Upper Airway Model

Sybrich Tiemersma, Stefan Minocchieri, Richard A. van Lingen, Mathias Nelle, Sunalene G. Devadason

Journal of Aerosol Medicine and Pulmonary Drug Delivery · 2012 · 28 citations · 14 references

Abstract

In a model for infant aerosol inhalation, we confirmed low lung dose using jet nebulizers and pMDI-holding chambers, whereas newer, more specialized vibrating membrane devices, designed specifically for use in preterm infants, deliver up to 20 times more drug to the infant's lung.

References

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