Delayed Maturation of Regenerating Myelinated Axons in Mice Lacking Neurofilaments

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.3K citations

Life Sciences, Biochemistry, Molecular Biology +12

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

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CNS stem cells express a new class of intermediate filament protein

Urban Lendahl, Lyle B. Zimmerman, Ronald D.G. McKay · Cell · 1990 · 3.2K citations

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

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Life Sciences, Biology, Genetics +16

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Medicine, Genetics, Molecular Genetics +15