Concepedia

Sustained release of low-dose ganciclovir from a silicone formulation prolonged the survival of rats with gliosarcomas under herpes simplex virus thymidine kinase suicide gene therapy

F. Miura, Shusuke Moriuchi, Miho Maeda, Akihiko Sano, Motohiko Maruno, Ana Maria Crous Tsanaclis, Renan Vieira Marino, Joseph C. Glorioso, Toshiki Yoshimine

Gene Therapy · 2002 · 16 citations · 13 references

DOI

Concepts

References

13

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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A Phase III Clinical Evaluation of Herpes Simplex Virus Type 1 Thymidine Kinase and Ganciclovir Gene Therapy as an Adjuvant to Surgical Resection and Radiation in Adults with Previously Untreated Glioblastoma Multiforme

N. G. Rainov · Human Gene Therapy · 2000 · 707 citations

, , +17

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

Zvi Ram, Kenneth W. Culver, Eric M. Oshiro et al. · Nature Medicine · 1997 · 683 citations

, , +16

Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo.

S H Chen, H. David Shine, J. Clay Goodman et al. · Proceedings of the National Academy of Sciences · 1994 · 481 citations

, , +17

National survey of patterns of care for brain-tumor patients

M. Stephen Mahaley, Curtis Mettlin, Nachimuthu Natarajan et al. · Journal of neurosurgery · 1989 · 388 citations

, , +16