EVALUATION OF A NEW PERFUSION SOLUTION FOR KIDNEY PRESERVATION

Abstract

We have compared the physical and biochemical properties of plasma and plasma protein fraction (PPF). We have found PPF to be a very satisfactory physiological hepatitis-free plasma substitute. Using PPF as a perfusion solution, we have preserved kidneys for 24 hr after up to 40 min of warm ischaemia and obtained immediate return of function on reimplantation. Perfusion with potassium-enriched plasma protein fraction (PPF2) prevented potassium leakage from the renal cells. Using PPF, we have avoided prefiltration, and we have been able to use a very simple and inexpensive perfusion apparatus.