Concepedia

Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway

Maolan Li, Zhou Zhang, Xiaoguang Li, Junyi Ye, Xiangsong Wu, Zhujun Tan, Chang Liu, Baiyong Shen, Wenguang Wu, Daizhan Zhou,

Nature Genetics · 2014 · 473 citations · 19 references

Concepts

MedicineGeneticsOncologyCancer GeneticsGenomicsMolecular OncologyBiliary Tract CancerCancer GenomicsCancer Molecular PathologyMolecular Tumor ProfilingNext-generation Sequencing In OncologyOncogenic Signaling PathwaysExome SequencingGallbladder CarcinomaTargeted Gene SequencingTargeted SequencingTumor Exome SequencingWhole Exome Sequencing StudiesWhole-exome Sequencing Analysis

References

19

Fast and accurate short read alignment with Burrows–Wheeler transform

Heng Li, Richard Durbin · Bioinformatics · 2009 · 62.8K citations · Full text

Life Sciences, Bioinformatics, Biology +12

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna, Matthew G. Hanna, Eric Banks et al. · Genome Research · 2010 · 30K citations · Full text

Life Sciences, Bioinformatics, Genetics +17

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

Pablo Cingolani, Adrian E. Platts, Le Lily Wang et al. · Fly · 2012 · 12.7K citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov, Serena Nik‐Zainal, David C. Wedge et al. · Nature · 2013 · 10.1K citations · Full text

Medicine, Cancer Biology, Oncology +14

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence, Petar Stojanov, Paz Polak et al. · Nature · 2013 · 5.7K citations · Full text

Medicine, Genetics, Oncology +14