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Synthesis and aldose reductase inhibitory activity of 5-arylidene-2,4-thiazolidinediones

Giuseppe Bruno, Luca Costantino, Carmela Curinga, Rosanna Maccari, Francesca Monforte, F. Nicolò, Rosaria Ottanà, Maria Gabriella Vigorita

Bioorganic & Medicinal Chemistry · 2002 · 256 citations · 24 references

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24

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

Timothy M. Willson, Jeffery E. Cobb, David J. Cowan et al. · Journal of Medicinal Chemistry · 1996 · 639 citations · Full text

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Studies on Antidiabetic Agents. X. Synthesis and Biological Activities of Pioglitazone and Related Compounds.

Yū Momose, Kanji Meguro, Hitoshi Ikeda et al. · Chemical and Pharmaceutical Bulletin · 1991 · 288 citations · Full text

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[[.omega.-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents

Barrie C. C. Cantello, Michael A. Cawthorne, Graham P. Cottam et al. · Journal of Medicinal Chemistry · 1994 · 266 citations

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A ‘specificity’ pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil

Alexandre Urzhumtsev, F. Favier, A. Mitschler et al. · Structure · 1997 · 232 citations · Full text

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Studies on antidiabetic agents. II. Synthesis of 5-(4-(1-methylcyclohexylmethoxy)-benzyl)thiazolidine-2,4-dione (ADD-3878) and its derivatives.

Takashi Sohda, Katsutoshi Mizuno, Eiko Imamiya et al. · Chemical and Pharmaceutical Bulletin · 1982 · 167 citations · Full text

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