Verapamil interaction with the muscarinic receptor: Stereoselectivity at two sites

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Modification of the binding properties of muscarinic receptors by gallamine.

Jane M. Stockton, N.J.M. Birdsall, A. S. V. Burgen et al. · Molecular Pharmacology · 1983 · 333 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Multiple effects of calcium antagonists on plateau currents in cardiac Purkinje fibers.

Robert S. Kass, Richard W. Tsien · The Journal of General Physiology · 1975 · 316 citations · Full text

Life Sciences, Cardiology, Physiology +17

Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.

Jeremy Z. Fields, William R. Roeske, Eugene Morkin et al. · Journal of Biological Chemistry · 1978 · 313 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?

J. Hescheler, D. Pelzer, G. Trube et al. · Pflügers Archiv - European Journal of Physiology · 1982 · 247 citations

Natural Sciences, Biophysics, Cardiology +12