Long-term repetitive mechanical loading of the knee joint by in vivo muscle stimulation accelerates cartilage degeneration and increases chondrocyte death in a rabbit model

The heat of shortening and the dynamic constants of muscle

Archibald Vivian Hill · Proceedings of the Royal Society of London. Series B, Biological sciences · 1938 · 5.6K citations

Natural Sciences, Biophysics, Physiology +14

Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips

Henry J. Mankin, HOWARD DORFMAN, Louis Lippiello et al. · Journal of Bone and Joint Surgery · 1971 · 2K citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

Tadashi Hayami, Maureen Pickarski, Ya Zhuo et al. · Bone · 2005 · 627 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology

Thomas Aigner, Alexander Zien, Angelika Gehrsitz et al. · Arthritis & Rheumatism · 2001 · 476 citations

Life Sciences, Cell Biology, Molecular Biology +17

Effects of mechanical loading on the tissues of the rabbit knee

Eric L. Radin, R. Bruce Martin, David B. Burr et al. · Journal of Orthopaedic Research® · 1984 · 401 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17