Genome-wide association study of CSF biomarkers Aβ _1-42 , t-tau, and p-tau _181p in the ADNI cohort

Abstract

In addition to known candidate genes, APOE, TOMM40, and one hypothetical gene LOC100129500 partially overlapping APOE; one novel gene, EPC2, and several other interesting genes were associated with CSF biomarkers that are related to AD. These findings, especially the new EPC2 results, require replication in independent cohorts.