Toxicity of Plutonium in Mice

Abstract

Plutonium citrate given intravenously to mice reduced life expectancy, decreased hemoglobin and leucocyte concentration in the peripheral blood, increased the incidence of liver degeneration, and induced osteogenic sarcomas. In none of these respects were the lowest dosage groups, 0.04 and 0.08 µc/kg, different from the control group.