Converting NADH to NAD+ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +12

Human Cells Lacking mtDNA: Repopulation with Exogenous Mitochondria by Complementation

Michael P. King, Giuseppe Attardi · Science · 1989 · 1.6K citations

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Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

Trends in Genetics · 1990 · 1.4K citations

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Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

Aleksandra Trifunović, Anna Hansson, Anna Wredenberg et al. · Proceedings of the National Academy of Sciences · 2005 · 555 citations · Full text

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Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

Hélène Pelicano, Rui‐Hua Xu, Min Du et al. · The Journal of Cell Biology · 2006 · 391 citations · Full text

Life Sciences, Cell Biology, Oncology +17