Adverse effects of alkali and acid on the anticoagulant potency of heparin, evaluated with methyl 2-deoxy-2-sulf- amino-α-d-glucopyranoside 3-sulfate as a model compound

Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin.

Ulf Lindahl, G. Bäckström, L Thunberg et al. · Proceedings of the National Academy of Sciences · 1980 · 489 citations · Full text

Life Sciences, Biochemistry, Carbohydrate Chemistry +16

Structure of the antithrombin-binding site in heparin.

Ulf Lindahl, G. Bäckström, Magnus Höök et al. · Proceedings of the National Academy of Sciences · 1979 · 366 citations · Full text

Life Sciences, Biochemistry, Glycobiology +14

Selective N-desulfation of heparin with dimethyl sulfoxide containing water or methanol

Yuko Inoue, Kinzo Nagasawa · Carbohydrate Research · 1976 · 215 citations

Natural Sciences, Biochemistry, Chemistry +5

Synthesis of heparin fragments. A chemical synthesis of the pentasaccharide O-(2-deoxy-2-sulfamido-6-O-sulfo-α-d-glucopyranosyl)-(1→4)-O-(β-d-glucopyranosyluronic acid)-(1→4)-O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-α-d-glucopyranosyl)-(1→4)-O-(2-O-sulfo-α-l-idopyranosyluronic acid)-(1→4)-2-deoxy-2-sulfamido-6-O-sulfo-d-glucopyranose decasodium salt, a heparin fragment having high affinity for antithrombin III

Maurice Petitou, Philippe Duchaussoy, Isidore Lederman et al. · Carbohydrate Research · 1986 · 145 citations

Life Sciences, Biochemistry, Chemistry +17

Novel regio- and stereoselective modifications of heparin in alkaline solution. Nuclear magnetic resonance spectroscopic evidence

Mahesh Jaseja, Rabindra Rej, F. Sauriol et al. · Canadian Journal of Chemistry · 1989 · 127 citations

Life Sciences, Biochemistry, Chemistry +8