Role of metabolism by intestinal microbiota in pharmacokinetics of oral baicalin

Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve

Win L. Chiou · Journal of Pharmacokinetics and Biopharmaceutics · 1978 · 623 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +14

Intestinal bacterial metabolism of flavonoids and its relation to some biological activities

Dong‐Hyun Kim, Eun-Ah Jung, In-Suk Sohng et al. · Archives of Pharmacal Research · 1998 · 392 citations

Life Sciences, Biochemistry, Microbiology +10

Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin.

Den‐En Shieh, Li‐Teh Liu, C.C. Lin · PubMed · 2000 · 343 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines

Shinichi Ikemoto, Kazunobu Sugimura, Naomasa Yoshida et al. · Urology · 2000 · 285 citations

Medicine, Oncology, Pharmacology +8

Pharmacokinetics of Berberine and Its Main Metabolites in Conventional and Pseudo Germ-Free Rats Determined by Liquid Chromatography/Ion Trap Mass Spectrometry

Feng Zuo, Norio Nakamura, Teruaki Akao et al. · Drug Metabolism and Disposition · 2006 · 281 citations

Pharmacy, Pharmacokinetics, Pharmacology +12