Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling in Cancer Causes Loss of Endothelial Fenestrations, Regression of Tumor Vessels, and Appearance of Basement Membrane Ghosts

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

K. Jin Kim, Bing Li, Jane Winer et al. · Nature · 1993 · 3.6K citations

Medicine, Cancer Biology, Oncology +14

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Gabriele Bergers, Rolf A. Brekken, Gerald McMahon et al. · Nature Cell Biology · 2000 · 2.8K citations · Full text

Medicine, Cancer Biology, Oncology +14

A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer

James Chih‐Hsin Yang, Leah Haworth, Richard M. Sherry et al. · New England Journal of Medicine · 2003 · 2.7K citations · Full text

Medicine, Oncology, Pharmacotherapy +17

Genes Expressed in Human Tumor Endothelium

Brad St. Croix, Carlo Rago, Victor E. Velculescu et al. · Science · 2000 · 1.8K citations

Medicine, Molecular Biology, Oncology +12

VEGF-Trap: A VEGF blocker with potent antitumor effects

Jocelyn Holash, Sam Davis, Susan D. Croll et al. · Proceedings of the National Academy of Sciences · 2002 · 1.7K citations

Medicine, Oncology, Pharmacology +17