Journal of Studies on Alcohol · 1999 · 41 citations · 26 references
Social SciencesPsychiatryPsychologyDevelopmental PsychologyDevelopmental PsychopathologyNeuropsychologyAlcohol DependenceAlcohol Use DisorderCognitive ImpairmentDevelopmental NeuropsychologyNeurocognitive DisordersPediatric NeuropsychologyAlcohol-related Cognitive ImpairmentDomain-specific Cognitive ProfilesHomogeneous GroupsNeuropsychological FunctioningNeuropsychological ImpairmentVisuospatial AbilitiesVisuospatial SkillsVulnerability
OBJECTIVE: The purpose of high-risk studies is to find characteristics that allow the identification of subjects with a higher vulnerability to alcoholism. The aim of this research was to verify if the familial density criterion is useful for subtyping children of alcoholics with different neuropsychological characteristics. METHOD: A battery of neuropsychological tests was administered to 102 boys and girls of 7-15 years of age; 66 were children of alcoholics with a high (n = 32) and low (n = 34) familial density of alcoholism, and 36 were children of nonalcoholic fathers with a negative family history of the disorder. The battery included tests to assess attention, visuospatial abilities and frontal functions. RESULTS: MANCOVAs showed that high-density children scored lower than children of nonalcoholic fathers in attentional and visuospatial tasks. There were no differences between low-density and negative family history children in these cognitive domains. CONCLUSIONS: These results suggest that children of alcoholics are not a homogeneous group. Children with multigenerational alcoholism, but not children with an alcoholic father, showed reduced performance in specific cognitive areas.
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The assessment and analysis of handedness: The Edinburgh inventory
R. C. Oldfield · Neuropsychologia · 1971 · 36.7K citations
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Wilma G. Rosen · Journal of Neuropsychiatry · 1996 · 278 citations