Chronic Binge Alcohol Administration Accentuates Expression of Pro‐Fibrotic and Inflammatory Genes in the Skeletal Muscle of Simian Immunodeficiency Virus–Infected Macaques

Abstract

The results of the study demonstrate SKM inflammation as an important underlying mechanism for muscle wasting. In addition, the study provides evidence of SKM fibrotic transformation as a factor in CBA-induced accentuation of SIV-associated muscle wasting.