Concepedia

pH-Responsive robust polymer micelles with metal–ligand coordinated core cross-links

Gyu Ha Hwang, Kyung Hyun Min, Hong Jae Lee, Hye Young Nam, Gi Hyun Choi, Byung Joo Kim, Seo Young Jeong, Sang Cheon Lee

Chemical Communications · 2014 · 54 citations · 22 references

DOI

Abstract

We report on pH-responsive core-shell polymer micelles with catechol-Fe(3+) coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

References

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