Concepedia

Synthesis and preliminary biological evaluation of MMP inhibitor radiotracers [11C]methyl-halo-CGS 27023A analogs, new potential PET breast cancer imaging agents

Qi-Huang Zheng, Xiangshu Fei, Xuan Liu, Ji-Quan Wang, Hui Sun, Bruce H. Mock, K. Lee Stone, Tanya D. Martinez, Kathy D. Miller, George W. Sledge,

Nuclear Medicine and Biology · 2002 · 76 citations · 26 references

DOI

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References

26

A simple synthesis of [11C]methyl triflate

Douglas M. Jewett · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 1992 · 344 citations

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Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli et al. · Journal of Medicinal Chemistry · 1997 · 325 citations · Full text

Highly Selective and Orally Active Inhibitors of Type IV Collagenase (MMP-9 and MMP-2):  <i>N</i>-Sulfonylamino Acid Derivatives

Yoshinori Tamura, Fumihiko Watanabe, Takuji Nakatani et al. · Journal of Medicinal Chemistry · 1998 · 283 citations · Full text

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Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3).

Hideaki Nagase, Cynthia G. Fields, Gregg B. Fields · Journal of Biological Chemistry · 1994 · 244 citations · Full text

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Carbonic Anhydrase and Matrix Metalloproteinase Inhibitors:  Sulfonylated Amino Acid Hydroxamates with MMP Inhibitory Properties Act as Efficient Inhibitors of CA Isozymes I, II, and IV, and <i>N</i>-Hydroxysulfonamides Inhibit Both These Zinc Enzymes

Andrea Scozzafava, Claudiu T. Supuran · Journal of Medicinal Chemistry · 2000 · 224 citations · Full text