Concepedia

Enzymatic detoxification of gluten by germinating wheat proteases: Implications for new treatment of celiac disease

S Stenman, Jarkko I. Venäläinen, Katri Lindfors, Seppo Auriola, Timo Mauriala, Anu Kaukovirta‐Norja, Anna Jantunen, Kaija Laurila, Shuo‐Wang Qiao, Ludvig M. Sollid,

Annals of Medicine · 2009 · 57 citations · 33 references

DOIFull text

Open access

Abstract

Germinating wheat enzymes reduce the toxicity of wheat gliadin in vitro and ex vivo. Further studies are justified to develop an alternative therapy for celiac disease.

References

33

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Lu Shan, Øyvind Molberg, Isabelle Parrot et al. · Science · 2002 · 1.6K citations

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Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

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