Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine

Nature

EngineeringNetwork ScienceP53 NetworkNetwork AnalysisInformation Forensics +3

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Yunje Cho, Svetlana S. Gorina, Philip D. Jeffrey, +1

Science

ChromatinCrystal StructureDna BindingStructural BioinformaticsBiomolecular Structure Prediction +13

Is p53 Polymorphism Maintained by Natural Selection?

G. Beckman, Richard Birgander, A. Sj auml lander, +4

Human Heredity

Allelic VariantMolecular EcologyCodon 72MedicineGenetics +11

Role of Cysteine Residues in Regulation of p53 Function

Robin Rainwater, Dorothy Parks, Mary E. Anderson, +2

Molecular and Cellular Biology

Molecular RegulationMolecular BiologyRedox BiologyTumor BiologyOxidative Stress +14

Mutations in p53 as potential molecular markers for human breast cancer.

Ingo B. Runnebaum, M Nagarajan, Mackenzie Bowman, +2

Proceedings of the National Academy of Sciences

Breast OncologyGeneticsPathologyHuman Breast CancerCancer Biology +16

Complete sequencing of TP53 predicts poor response to systemic therapy of advanced breast cancer.

E. Berns, John A. Foekens, R. van Vossen, +11

PubMed

Breast OncologyPathologyComplete SequencingSystemic TherapyCancer Biology +17

Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.

David H.‐F. Teng, William L. Perry, James K. Hogan, +21

PubMed

Signal Transduction PathwaysHuman Mitogen-activated ProteinCell DeathCandidate Tumor SuppressorCancer Biology +17

Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.

Gloria H. Su, Werner Hilgers, Manu C. Shekher, +4

PubMed

PathologyP38 MapkCancer BiologyTumor BiologyPancreatic Cancer +15

Mdm-2: “big brother” of p53

Jamil Momand, Gerard P. Zambetti

Journal of Cellular Biochemistry

Tumor BiologyCancer Cell BiologyCancer GenomicsTumor SuppressorCancer Genetics +3

Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling.

M van de Wetering, Nick Barker, I C Harkes, +6

PubMed

Breast OncologyTcf Reporter GeneCancer BiologyTumor BiologySignaling Pathway +14