Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Darren A.E. Cross, Dario R. Alessi, Philip Cohen, +2

Nature

Signal TransductionMolecular PhysiologyBiochemistryInsulin ManagementDiabetes +8

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

Edgar Schreiber, Patrick Matthias, Michael M. Müller, +1

Nucleic Acids Research

‘ Mini ExtractsOctamer Binding ProteinsMolecular BiologyAnalytical UltracentrifugationRapid Detection +15

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Osamu Tetsu, Frank McCormick

Nature

Cancer ResearchOncologyColon Carcinoma CellsGastrointestinal OncologyMedicine +8

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin, +5

Science

Tcf Reporter GenePathologyCancer BiologyTumor BiologyConstitutive Transcriptional Activation +16

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui, +1

Journal of Biological Chemistry

Specific InhibitorMolecular PharmacologyMedicinal ChemistrySignaling PathwayReceptor Tyrosine Kinase +14

Mechanism of activation of protein kinase B by insulin and IGF-1.

Dario R. Alessi, Mirjana Andjelković, B. Caudwell, +4

The EMBO Journal

Molecular PhysiologySignal TransductionSignaling PathwayGrowth HormoneDiabetes +7

Identification and characterization of the familial adenomatous polyposis coli gene

Joanna Groden, Andrew Thliveris, Wade S. Samowitz, +20

Cell

Molecular EpidemiologyGenetic DisorderMedicineGeneticsPathogenesis +8

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker, +2

Proceedings of the National Academy of Sciences

Signal TransductionPd 098059Cell RegulationSignaling PathwayMedicine +12

β-catenin is a target for the ubiquitin–proteasome pathway

Hermann Aberle, Andreas Bauer, Jörg Stappert, +2

The EMBO Journal

Protein FunctionMolecular RegulationMedicineProteasomeProtein Degradation +4

Phosphatidylinositol-3-OH kinase direct target of Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Ritu Dhand, +5

Nature

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseCellular BiochemistryMedicine +3