Identification of Proteolipid from an Extremely Halophilic ArchaeonHalobacterium salinarumas anN,N′-Dicyclohexyl-carbodiimide Binding Subunit of ATP Synthase

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.4K citations · Full text

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 22.9K citations

Protein Chemistry, Biochemistry, Simple Method +12

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

Hermann Schägger, Gebhard von Jagow · Analytical Biochemistry · 1987 · 11.5K citations

Protein Chemistry, Biochemistry, Natural Sciences +8

Complete Genome Sequence of the Methanogenic Archaeon, <b> <i>Methanococcus jannaschii</i> </b>

Carol J. Bult, Owen White, Gary J. Olsen et al. · Science · 1996 · 2.1K citations

Biology, Microbial Systematics, Whole-genome Random Sequencing +15