IEEE Transactions on Medical Imaging · 2014 · 37 citations · 30 references
ComputingBiomedical EngineeringComputer ScienceBiomedical ImagingComputer VisionDiagnostic Imaging3D Imaging3D ReconstructionDiagnostic Imaging SystemsMedical Image AnalysisMedical ImagingOptical Flow3D Surface Modeling3D Tumor DetectionBreast Phantom StudiesBreast Tumor SegmentationModel-based SegmentationStiffnessThree-dimensional Breast ImagingThree-dimensional Motion Capture
Digital image-based elasto-tomography (DIET) is a prototype system for breast cancer screening. A breast is imaged while being vibrated, and the observed surface motion is used to infer the internal stiffness of the breast, hence identifying tumors. This paper describes a computer vision system for accurately measuring 3-D surface motion. A model-based segmentation is used to identify the profile of the breast in each image, and the 3-D surface is reconstructed by fitting a model to the profiles. The surface motion is measured using a modern optical flow implementation customized to the application, then trajectories of points on the 3-D surface are given by fusing the optical flow with the reconstructed surfaces. On data from human trials, the system is shown to exceed the performance of an earlier marker-based system at tracking skin surface motion. We demonstrate that the system can detect a 10 mm tumor in a silicone phantom breast.
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