Application of the Intramolecular α-Amidoalkylation Reaction for the Synthesis of 2-Arylsulfonyl-1,2,3,4-tetrahydroisoquinolines

L. K. Lukanov, Atanas P. Venkov, N. M. Mollov

Synthesis · 1987 · 22 citations · 0 references

Concepts

Abstract

The adducts of azomethines and sulfonyl chlorides (Method A) as well as hydroxymethylated sulfonamides (Method B) are used for the synthesis of 2-arylsulfonyl-1,2,3,4-tetrahydroisoquinolines 4a-q.