Application of the Intramolecular α-Amidoalkylation Reaction for the Synthesis of 2-Arylsulfonyl-1,2,3,4-tetrahydroisoquinolines - Concepedia

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Application of the Intramolecular α-Amidoalkylation Reaction for the Synthesis of 2-Arylsulfonyl-1,2,3,4-tetrahydroisoquinolines

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References

1987

Year

L. K. Lukanov, Atanas P. Venkov, N. M. Mollov

Sulfonyl ChloridesMethod BHeterocyclicMethod AOrganic ChemistryChemistryHeterocycle ChemistryPharmacologySynthetic ChemistryEnantioselective SynthesisIntramolecular α-Amidoalkylation Reaction

Abstract

The adducts of azomethines and sulfonyl chlorides (Method A) as well as hydroxymethylated sulfonamides (Method B) are used for the synthesis of 2-arylsulfonyl-1,2,3,4-tetrahydroisoquinolines 4a-q.