Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

A simplified system for generating recombinant adenoviruses

Tong‐Chuan He, Shibin Zhou, Luís Teixeira da Costa et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

Life Sciences, Biotechnology, Molecular Biology +15

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Seung Hee Yoo, Shin Yamazaki, Phillip L. Lowrey et al. · Proceedings of the National Academy of Sciences · 2004 · 2.4K citations · Full text

Nursing, Neuroscience, Physiology +17

Manipulating the mouse embryo: A laboratory manual

Martin Johnson · Trends in Genetics · 1986 · 2.3K citations

Veterinary Medicine, Cell Biology, Developmental Biology +12

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Nicolas Preitner, Francesca Damiola, Luis Lopez‐Molina et al. · Cell · 2002 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Resetting Central and Peripheral Circadian Oscillators in Transgenic Rats

Shin Yamazaki, Rika Numano, Michikazu Abe et al. · Science · 2000 · 1.9K citations

Nursing, Biology, Physiology +17