Characterization of the aryl hydrocarbon receptor repressor gene and association of its Pro185Ala polymorphism with micropenis

Hideki Fujita, Rika Kosaki, Hiroshi Yoshihashi, Tsutomu Ogata, Masaru Tomita, Tomonobu Hasegawa, Takao Takahashi, Nobutake Matsuo, Kenjiro Kosaki

Teratology · 2002 · 48 citations · 45 references

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Abstract

Homozygosity for the 185Pro allele of AHRR may increase the susceptibility of a fetus to the undermasculinizing effects of dioxin exposure in utero, presumably through the diminished inhibition of AHR-mediated signaling.

References

45