Concepedia

Synthesis and biological activity of novel MIF antagonists

Sarala Balachandran, Pradip K. Gadekar, Santosh Parkale, Vitthal N. Yadav, Divya Kamath, Sneha Ramaswamy, Somesh Sharma, Ram A. Vishwakarma, Nilesh M. Dagia

Bioorganic & Medicinal Chemistry Letters · 2011 · 16 citations · 9 references

DOI

Concepts

References

9

ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis

Yousef Al‐Abed, Darrin Dabideen, Bayan Aljabari et al. · Journal of Biological Chemistry · 2005 · 313 citations · Full text

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A functional heteromeric MIF receptor formed by CD74 and CXCR4

Verena Schwartz, Hongqi Lue, Sandra Kraemer et al. · FEBS Letters · 2009 · 237 citations · Full text

, , +17

Macrophage migration inhibitory factor

John A. Baugh, Richard Bucala · Critical Care Medicine · 2002 · 225 citations

, , +8

Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites

Peter D. Senter, Yousef Al‐Abed, Christine N. Metz et al. · Proceedings of the National Academy of Sciences · 2002 · 168 citations · Full text

, , +13

A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation

Günter Fingerle-Rowson, Dayananda Rao Kaleswarapu, Corinna Schlander et al. · Molecular and Cellular Biology · 2009 · 148 citations · Full text

, , +15