British Journal of Clinical Pharmacology · 1992 · 12 citations · 0 references
MedicineInternal MedicineClinical MedicineClinical Trial PhasesClinical TrialsPatient SelectionStudy DesignVolunteer ScreeningVolunteer SelectionPhase I Clinical TrialsSafe ConductSelectionTrial SamplingVolunteer Selection Validity
The safe conduct of phase I volunteer studies requires careful selection and screening of volunteers. We have reviewed the results of the selection procedure in our clinic. The information received from the volunteer's general practitioner revealed clinical problems which had not been disclosed during medical history or examination.