Global Estimates of Prevalent and Incident Herpes Simplex Virus Type 2 Infections in 2012

Abstract

The global burden of HSV-2 infection is large, leaving over 400 million people at increased risk of genital ulcer disease, HIV acquisition, and transmission of HSV-2 to partners or neonates. These estimates highlight the critical need for development of vaccines, microbicides, and other new HSV prevention strategies.