Complementation Analysis of Carnitine Palmitoyltransferase I and II Defects

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

Julie McGarry, G.F. Leatherman, Daniel W. Foster · Journal of Biological Chemistry · 1978 · 602 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11

Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

Julie McGarry, Stanley E. Mills, Carlin S. Long et al. · Biochemical Journal · 1983 · 556 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +9

Muscle Carnitine Palmityltransferase Deficiency and Myoglobinuria

Salvatore DiMauro, Paola M. Melis DiMauro · Science · 1973 · 478 citations

Life Sciences, Biochemistry, Genetics +14

Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.

M S Murthy, S.V. Pande · Proceedings of the National Academy of Sciences · 1987 · 243 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyltransferase I. Direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function.

Victoria Esser, Charles H. Britton, B C Weis et al. · Journal of Biological Chemistry · 1993 · 220 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5