Elimination of a Quaternary Pyridinium Salt Delivered as Its Dihydropyridine Derivative from Brain of Mice

Soman and Sarin: Clinical Manifestations and Treatment of Accident of Accidental Poisoning by Organophosphates

Frederick R. Sidell · Clinical toxicology · 1974 · 208 citations

Pharmacy, Clinical Toxicology, Toxicology +14

Active transport of quaternary ammonium compounds by the choroid plexus in vitro

Yoshihiro Tochino, Lewis S. Schanker · American Journal of Physiology-Legacy Content · 1965 · 80 citations

Medicine, Biochemistry, Pharmacology +14

Delivery of a Quaternary Pyridinium Salt Across the Blood-Brain Barrier by Its Dihydropyridine Derivative

Nicholas Bodor, Efraim Shek, Tsunehiko Higuchi · Science · 1975 · 74 citations

Pharmacy, Neuroscience, Pharmacology +14

Improved delivery through biological membranes. 1. Synthesis and properties of 1-methyl-1,6-dihydropyridine-2-carbaldoxime, a pro-drug of N-methylpyridinium-2-carbaldoxime chloride

Nicolae Bodor, Efraim Shek, Takeru Higuchi · Journal of Medicinal Chemistry · 1976 · 64 citations

Engineering, Pharmaceutics, Pharmacology +15

Improved delivery through biological membranes. 3. Delivery of N-methylpyridinium-2-carbaldoxime chloride through the blood-brain barrier in its dihydropyridine pro-drug form

Efraim Shek, Takeru Higuchi, Nicolae Bodor · Journal of Medicinal Chemistry · 1976 · 51 citations

Pharmacy, Pharmaceutics, Pharmacology +17