Urinary 8-hydroxydeoxyguanosine is elevated in patients with nephrolithiasis

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

César G. Fraga, Mark K. Shigenaga, J W Park et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.

Eun‐Mi Park, Mark K. Shigenaga, Paolo Degan et al. · Proceedings of the National Academy of Sciences · 1992 · 291 citations

Life Sciences, Biochemistry, Molecular Biology +14

Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate cancers

Chiuan-Chian Chiou, Pi-Yueh Chang, Err–Cheng Chan et al. · Clinica Chimica Acta · 2003 · 274 citations

Medicine, Oncology, Urology +17

Biomarker evidence of DNA oxidation in lung cancer patients: association of urinary 8‐hydroxy‐2′‐deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment

Marina Erhola, Shinya Toyokuni, K. Okada et al. · FEBS Letters · 1997 · 265 citations · Full text

Medicine, Cancer Biology, Oncology +13

Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia

P A Courtney, A. D. Crockard, K Williamson et al. · Annals of the Rheumatic Diseases · 1999 · 232 citations · Full text

Life Sciences, Immunology, Pathology +17