Activation of ATP-Sensitive Potassium Channels: A Novel Pharmacological Approach to Myocardial Protection?

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

Victoria M. Bolotina, Soheil Najibi, James Palacino et al. · Nature · 1994 · 1.7K citations

Natural Sciences, Biophysics, Physiology +12

Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs.

G J Gross, John A. Auchampach · Circulation Research · 1992 · 949 citations

Medicine, Cardiology, Pharmacology +16

ATP-sensitive K+ channel in the mitochondrial inner membrane

I Inoue, Hideki Nagase, Tomihiko Higuti · Nature · 1991 · 753 citations

Life Sciences, Biochemistry, Biophysics +14

ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage.

William C. Cole, Cadence Mcpherson, David Sontag · Circulation Research · 1991 · 471 citations · Full text

Medicine, Cardiology, Physiology +17

Effects of the KATP channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs.

Zhenhai Yao, G J Gross · Circulation · 1994 · 255 citations

Medicine, Cardiology, Pharmacology +17